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Archive for January, 2010

The Use of Drugs and Nutritional Supplements in Top-Level Track and Field Athletes

Sunday, January 31st, 2010

Philippe Tscholl, MD*, Juan M. Alonso, MD§, Gabriel Dollé, MD, Astrid Junge, PhD|| and Jiri Dvorak, MD||

Abstract

Background High use of medication and nutritional supplements has been reported in several sports.

Purpose To document the use of prescribed medication and nutritional supplements in female and male junior, youth, and adult track and field athletes depending on their sports discipline.

Study Design Descriptive epidemiology study.

Methods Analysis of 3 887 doping control forms undertaken during 12 International Association of Athletics Federations World Championships and 1 out-of-competitions season in track and field.

Results There were 6 523 nutritional supplements (1.7 per athlete) and 3 237 medications (0.8 per athlete) reported. Nonsteroidal anti-inflammatory drugs (NSAIDs; 0.27 per athlete, n = 884), respiratory drugs (0.21 per athlete, n = 682), and alternative analgesics (0.13, n = 423) were used most frequently. Medication use increased with age (0.33 to 0.87 per athlete) and decreased with increasing duration of the event (from sprints to endurance events; 1.0 to 0.63 per athlete). African and Asian track and field athletes reported using significantly fewer supplements (0.85 vs 1.93 per athlete) and medications (0.41 vs 0.96 per athlete) than athletes from other continents. The final ranking in the championships was unrelated to the quantity of reported medications or supplements taken. Compared with middle-distance and long-distance runners, athletes in power and sprint disciplines reported using more NSAIDs, creatine, and amino acids, and fewer antimicrobial agents.

Conclusion The use of NSAIDs in track and field is less than that reported for team-sport events. However, nutritional supplements are used more than twice as often as they are in soccer and other multisport events; this inadvertently increases the risk of positive results of doping tests.

Clinical Relevance It is essential that an evidence-based approach to the prescribing of medication and nutritional supplements is adopted to protect the athletes’ health and prevent them from testing positive in doping controls.

Correction of Posterior Shoulder Tightness Is Associated With Symptom Resolution in Patients With Internal Impingement

Sunday, January 31st, 2010

Timothy F. Tyler, PT, ATC*, Stephen J. Nicholas, MD, Steven J. Lee, MD, Michael Mullaney, PT and Malachy P. McHugh, PhD

Abstract

Background Glenohumeral internal rotation deficit (GIRD) and posterior shoulder tightness have been linked to internal impingement.

Purpose To determine if improvements in GIRD and/or decreased posterior shoulder tightness are associated with a resolution of symptoms.

Study Design Cohort study; Level of evidence, 3.

Methods Passive internal rotation and external rotation (ER) range of motion (ROM) at 90° of shoulder abduction and posterior shoulder tightness (cross-chest adduction in side lying) were assessed in 22 patients with internal impingement (11 men, 11 women; age 41 ± 13 years). Treatment involved stretching and mobilization of the posterior shoulder. The Simple Shoulder Test (SST) was administered on initial evaluation and discharge. Changes in GIRD, ER ROM, and posterior shoulder tightness were compared between patients with complete resolution of symptoms versus patients with residual symptoms using independent t tests.

Results Patients had significant GIRD (35°), loss of ER ROM (23°), and posterior shoulder tightness (35°) on initial evaluation (all P < .01). Physical therapy (7 ± 2 weeks; range, 3–12 weeks) improved GIRD (26° ± 14°; P < .01), ER ROM loss (14° ± 20°), and posterior shoulder tightness (27° ±19°). The SST improved from 5 ± 3 to 11 ± 1 (P < .01). A greater improvement in posterior shoulder tightness was seen in patients with complete resolution of symptoms (n = 12) compared with patients with residual symptoms (35° vs 18°; P < .05). Improvements in GIRD and ER ROM loss were not different between groups (GIRD, 25° vs 28°, P = .57; ER ROM, 14° vs 15°, P = .84).

Conclusion Resolution of symptoms after physical therapy treatment for internal impingement was related to correction of posterior shoulder tightness but not correction of GIRD.

Arthroscopic Labral Repair and Treatment of Femoroacetabular Impingement in Professional Hockey Players

Sunday, January 31st, 2010

Marc J. Philippon, MD*, Douglass R. Weiss, MD, David A. Kuppersmith, Karen K. Briggs, MPH and Connor J. Hay

Abstract

Background Hip injuries are common among professional hockey players in the National Hockey League (NHL).

Hypothesis Professional hockey players will return to a high level of function and ice hockey after arthroscopic labral repair and treatment of femoroacetabular impingement.

Study Design Case series; Level of evidence, 4.

Methods Twenty-eight professional hockey players (NHL) were unable to perform at the professional level due to unremitting and debilitating hip pain. Players underwent arthroscopic labral repair and were treated for femoroacetabular impingement from March 2005 to December 2007. Players who had bilateral hip symptoms were excluded. Athletes completed the Modified Harris Hip Score preoperatively and postoperatively and also completed a patient satisfaction questionnaire postoperatively. Return to sport was defined as the player resuming skating for training or participation in the sport of ice hockey.

Results The average age at the time of surgery was 27 years (range, 18–37). There were 11 left hips and 17 right hips. Player positions included 9 defensemen, 12 offensive players, and 7 goaltenders. All players had labral lesions that required repair. In addition, all patients had evidence of femoroacetabular impingement at the time of surgery. The average time to return to skating/hockey drills was 3.4 months. The average time to follow-up was 24 months (range, 12–42). The Modified Harris Hip Score improved from 70 (range, 57–100) preoperatively to an average of 95 (range, 74–100) at follow-up. The median patient satisfaction was 10 (range, 5–10). Two players had reinjury and required additional hip arthroscopy.

Conclusion Treatment of femoroacetabular impingement and labral lesions in professional hockey players resulted in successful outcomes, with high patient satisfaction and prompt return to sport.

Return to Sports Participation After Articular Cartilage Repair in the Knee Scientific Evidence

Saturday, January 30th, 2010

Background Articular cartilage injury in the athlete’s knee presents a difficult clinical challenge. Despite the importance of returning injured athletes to sports, information is limited on whether full sports participation can be successfully achieved after articular cartilage repair in the knee.

Hypothesis Systematic analysis of athletic participation after articular cartilage repair will demonstrate the efficacy of joint surface restoration in high-demand patients and help to optimize outcomes in athletes with articular cartilage injury of the knee.

Study Design Systematic review.

Methods A comprehensive literature review of original studies was performed to provide information about athletic participation after articular cartilage repair. The athlete’s ability to perform sports postoperatively was assessed by activity outcome scores, rate of return to sport, timing of the return, level of postoperative sports participation, and the continuation of athletic activity over time.

Results Twenty studies describing 1363 patients were included in the review, with an average follow-up of 42 months. Return to sports was possible in 73% overall, with highest return rates after osteochondral autograft transplantation. Time to return to sports varied between 7 and 18 months, depending on the cartilage repair technique. Initial return to sports at the preinjury level was possible in 68% and did not significantly vary between surgical techniques. Continued sports participation at the preinjury level was possible in 65%, with the best durability after autologous chondrocyte transplantation. Several factors affected the ability to return to sport: athlete’s age, preoperative duration of symptoms, level of play, lesion size, and repair tissue morphology.

Conclusion Articular cartilage repair in the athletic population allows for a high rate of return to sports, often at the preinjury level. Return to sports participation is influenced by several independent factors. The findings provide pertinent information that is helpful for the clinical decision-making process and for the management of the athlete’s postoperative expectations.

  1. Kai Mithoefer, MD*,
  2. Karen Hambly, PT, MCSP§,
  3. Stefano Della Villa, MD||,
  4. Holly Silvers, MPT and
  5. Bert R. Mandelbaum, MD
  6. Kai Mithoefer, MD*,
  7. Karen Hambly, PT, MCSP§,
  8. Stefano Della Villa, MD||,
  9. Holly Silvers, MPT and
  10. Bert R. Mandelbaum, MD

Anatomy of Normal Human Anterior Cruciate Ligament Attachments Evaluated by Divided Small Bundles

Saturday, January 30th, 2010

Background Double-bundle anterior cruciate ligament (ACL) reconstruction has several potential advantages over single-bundle reconstruction with hamstring tendons. However, there are still controversies regarding tunnel placement in tibial and femoral attachments.

Hypothesis The macroscopically normal ACL consists of small bundles about 1 mm in diameter. Detailed observation of the divided smaller bundles will achieve better understanding of the tunnel placement in anatomic ACL reconstruction.

Study Design Descriptive laboratory study.

Methods This study used 20 cadaveric knees. The ACL was divided into anteromedial and posterolateral bundles, then separated into 10 small bundles of 2-mm diameters, with preservation of their attachment sites marked with color markers. The positional relationship between the femoral and tibial attachments of each small bundle was investigated.

Results A layered positional correlation of small bundles was found between the tibial and femoral attachments. Small bundles aligned in the anterior-posterior direction in the tibia corresponded to the bundles aligned in a high-low direction in the femur in flexion. The femoral attachment pattern was relatively similar in each specimen; however, the tibial attachment showed 2 patterns: an oblique type (12 of 20) and a transverse type (8 of 20). The posterior portion of the posterolateral bundle was separately attached to the medial and lateral portions of the tibial attachment. There was no fibrous insertion in the center of the posterior portion of the ACL tibial attachment in any specimen. In this bare area, there was fat tissue and vascular bundles.

Conclusion Small bundles constituting the ACL showed a relatively layered arrangement between 2 attachments. The tibial attachment showed 2 patterns of oblique and transverse types, and the vascular bundles were located in the center of the posterolateral bundle.

Clinical Relevance The results of this study of the normal ACL will provide insights for surgeons when placing grafts during anatomic ACL reconstruction.

  1. Kenji Hara, MD, PhD*,
  2. Tomoyuki Mochizuki, MD, PhD*,
  3. Ichiro Sekiya, MD, PhD*,
  4. Kumiko Yamaguchi, MD, PhD,
  5. Keiichi Akita, MD, PhD and
  6. Takeshi Muneta, MD, PhD*§||

The Use of Drugs and Nutritional Supplements in Top-Level Track and Field Athletes

Saturday, January 30th, 2010

Background High use of medication and nutritional supplements has been reported in several sports.

Purpose To document the use of prescribed medication and nutritional supplements in female and male junior, youth, and adult track and field athletes depending on their sports discipline.

Study Design Descriptive epidemiology study.

Methods Analysis of 3 887 doping control forms undertaken during 12 International Association of Athletics Federations World Championships and 1 out-of-competitions season in track and field.

Results There were 6 523 nutritional supplements (1.7 per athlete) and 3 237 medications (0.8 per athlete) reported. Nonsteroidal anti-inflammatory drugs (NSAIDs; 0.27 per athlete, n = 884), respiratory drugs (0.21 per athlete, n = 682), and alternative analgesics (0.13, n = 423) were used most frequently. Medication use increased with age (0.33 to 0.87 per athlete) and decreased with increasing duration of the event (from sprints to endurance events; 1.0 to 0.63 per athlete). African and Asian track and field athletes reported using significantly fewer supplements (0.85 vs 1.93 per athlete) and medications (0.41 vs 0.96 per athlete) than athletes from other continents. The final ranking in the championships was unrelated to the quantity of reported medications or supplements taken. Compared with middle-distance and long-distance runners, athletes in power and sprint disciplines reported using more NSAIDs, creatine, and amino acids, and fewer antimicrobial agents.

Conclusion The use of NSAIDs in track and field is less than that reported for team-sport events. However, nutritional supplements are used more than twice as often as they are in soccer and other multisport events; this inadvertently increases the risk of positive results of doping tests.

Clinical Relevance It is essential that an evidence-based approach to the prescribing of medication and nutritional supplements is adopted to protect the athletes’ health and prevent them from testing positive in doping controls.

  1. Philippe Tscholl, MD*,
  2. Juan M. Alonso, MD§,
  3. Gabriel Dollé, MD,
  4. Astrid Junge, PhD|| and
  5. Jiri Dvorak, MD||

Influence of Age, Sex, Technique, and Exercise Program on Movement Patterns After an Anterior Cruciate Ligament Injury Prevention Program in Youth Soccer Players

Wednesday, January 27th, 2010

Abstract

Background Anterior cruciate ligament (ACL) injury prevention programs show promising results with changing movement; however, little information exists regarding whether a program designed for an individual’s movements may be effective or how baseline movements may affect outcomes.

Hypothesis A program designed to change specific movements would be more effective than a “one-size-fits-all” program. Greatest improvement would be observed among individuals with the most baseline error. Subjects of different ages and sexes respond similarly.

Study Design Randomized controlled trial; Level of evidence, 1.

Methods One hundred seventy-three youth soccer players from 27 teams were randomly assigned to a generalized or stratified program. Subjects were videotaped during jump-landing trials before and after the program and were assessed using the Landing Error Scoring System (LESS), which is a valid clinical movement analysis tool. A high LESS score indicates more errors. Generalized players performed the same exercises, while the stratified players performed exercises to correct their initial movement errors. Change scores were compared between groups of varying baseline errors, ages, sexes, and programs.

Results Subjects with the highest baseline LESS score improved the most (95% CI, −3.4 to −2.0). High school subjects (95% CI, −1.7 to −0.98) improved their technique more than pre–high school subjects (95% CI, −1.0 to −0.4). There was no difference between the programs or sexes.

Conclusions Players with the greatest amount of movement errors experienced the most improvement. A program’s effectiveness may be enhanced if this population is targeted.

  1. Lindsay J. DiStefano, ATC, MA*,
  2. Darin A. Padua, ATC, PhD,
  3. Michael J. DiStefano, ATC, MA and
  4. Stephen W. Marshall, PhD

Knee Immobilization for Pain Control After a Hamstring Tendon Anterior Cruciate Ligament Reconstruction A Randomized Clinical Trial

Wednesday, January 27th, 2010

Abstract

Background This study will attempt to evaluate the efficacy of knee immobilization on patient pain levels after an anterior cruciate ligament reconstruction.

Hypothesis There is no difference in visual analog scale pain scores 2 days after anterior cruciate ligament reconstruction between patients who wear a knee immobilizer and those who do not wear a knee immobilizer.

Study Design Randomized clinical trial; Level of evidence, 1.

Methods Patients aged 18 to 40 years who met study inclusion criteria were eligible. Patients meeting intraoperative inclusion critiera were randomized (immobilizer or no immobilizer) after wound closure. The immobilizer used was a soft, unhinged brace with Velcro® straps. Preoperative, intraoperative, and postoperative protocols were standardized. The primary outcome was patient self-assessed pain using a 0-to-100-mm visual analog scale at day 2 after surgery. Secondary outcomes included pain and analgesic use in the first 14 days after surgery, complications, and range of motion (approximately 3 weeks postoperatively). A sample size estimate was calculated and resulted in the need for 44 patients per group.

Results A total of 102 patients were enrolled; 88 patients were randomized, and 14 were excluded intraoperatively. There was no difference in mean visual analog scale pain scores at 2 days after surgery between immobilized and nonimmobilized patients (32.6 and 35.2, respectively; P = .59; difference, −2.6; 95% confidence interval, −12.2 to 6.9). There were no differences between groups in medication consumed, range of motion, or complications. Pain and analgesic use were the same for both groups at 7 and 14 days postoperatively.

Conclusion No differences in pain or any of the secondary outcomes were detected between immobilized and nonimmobilized patients at any point during the first 14 days after anterior cruciate ligament reconstruction.

  1. Laurie A. Hiemstra, MD, PhD, FRCS(C)*,
  2. S. Mark Heard, MD, FRCS(C),
  3. Treny M. Sasyniuk, MSc,
  4. Greg L. Buchko, MD, FRCS(C),
  5. Jeremy G. Reed, MD, FRCS(C) and
  6. Bradley J. Monteleone, MD, MSc, PhD, Dip Sport Med

Does Intensive Rehabilitation Permit Early Return to Sport Without Compromising the Clinical Outcome After Arthroscopic Autologous Chondrocyte Implantation in Highly Competitive Athletes?

Wednesday, January 27th, 2010

Abstract

Background Despite improvement in treatment for articular cartilage lesions, prolonged recovery still precludes early return to competitive sports. The challenge of postoperative rehabilitation is to optimize return to preinjury activities without jeopardizing the graft.

Hypothesis Intensive rehabilitation after second-generation arthroscopic autologous cartilage implantation (Hyalograft C) facilitates graft maturation and safely allows for early return to competition without jeopardizing clinical outcome at longer follow-up.

Study Design Cohort study; Level of evidence, 3.

Methods The outcome of 31 competitive male athletes with International Cartilage Repair Society grade III–IV cartilaginous lesions of the medial or lateral femoral condyle or trochlea were evaluated at 1-, 2-, and 5-year follow-up. The athletic cohort was compared with a similar control cohort of 34 nonathletic patients who were treated with autologous chondrocyte implantation. The athletic cohort followed a 4-phase intensive rehabilitation protocol. Eleven of the patients in this cohort were also treated with an isokinetic exercise program and on-field rehabilitation. The patients in the control cohort completed only phase 1 of rehabilitation.

Results When comparing the 2 groups, a greater improvement in the group of athletes was achieved at 5-year follow-up (P = .037) in the self-assessment of quality of life and International Knee Documentation Committee subjective evaluation at 12 months and at 5 years of follow-up (P = .001 and P = .002, respectively). When analyzing the return to sports activity, 80.6% of the athletes returned to their previous activity level in 12.4 ± 1.6 months; athletes treated with the on-field rehabilitation and isokinetic exercise program had faster recovery and an even earlier return to competition (10.6 ± 2.0 months).

Conclusion For optimal results, autologous chondrocyte implantation rehabilitation should not only follow but also facilitate the process of graft maturation. Intensive rehabilitation may safely allow a faster return to competition and also influence positively the clinical outcome at medium-term follow-up.

  1. Stefano Della Villa, MD*,
  2. Elizaveta Kon, MD,
  3. Giuseppe Filardo, MD,
  4. Margherita Ricci, MD*,
  5. Ferruccio Vincentelli, MD*,
  6. Marco Delcogliano, MD§ and
  7. Maurilio Marcacci, PhD

Shallow Medial Tibial Plateau and Steep Medial and Lateral Tibial Slopes New Risk Factors for Anterior Cruciate Ligament Injuries

Wednesday, January 27th, 2010

Abstract

Background The geometry of the tibial plateau has been largely ignored as a source of possible risk factors for anterior cruciate ligament injury. Discovering the anterior cruciate ligament injury risk factors associated with the tibial plateau may lead to delineation of the existing sex-based disparity in anterior cruciate ligament injuries and help develop strategies for the prevention of anterior cruciate ligament injuries regardless of gender.

Hypothesis Individuals with a shallower medial tibial depth of concavity, while having increased posteriorly directed slope of their tibial plateau, are at increased risk of suffering an anterior cruciate ligament injury compared with those with decreased posterior slope and increased medial tibial depth. Furthermore, these relationships are different between men and women.

Study Design Case-control study (prevalence); Level of evidence, 3.

Methods The medial, lateral, and coronal tibial plateau slopes as well as the medial tibial depth of concavity in 55 uninjured controls (33 women and 22 men) and 49 anterior cruciate ligament–injured cases (27 women and 22 men) were measured using magnetic resonance images. First, a preliminary t test was performed to establish any existing differences between groups. Next, a logistic regression model was developed to determine the probability of anterior cruciate ligament injury in an individual based on the measured covariates.

Results The female anterior cruciate ligament–injured cases had increased lateral tibial slope (P = .03) and shallower medial tibial depth (P = .0003) compared with the uninjured controls, while male cases had increased lateral and medial tibial slope (P = .02) and shallower medial tibial depth (P = .0004) compared with controls. The logistic regression analysis and odds ratio estimates showed that medial tibial depth is an important risk factor (odds ratio = 3.03 per 1 mm decrease in its value), followed by lateral tibial slope (odds ratio = 1.17 per 1° increase in its value) in all participants. The medial tibial slope (odds ratio = 1.18 per 1° increase in its value) was a risk factor only in men.

Conclusion A combination of increased posterior-directed tibial plateau slope and shallow medial tibial plateau depth could be a major risk factor in anterior cruciate ligament injury susceptibility regardless of gender. Different injury risk models may be needed for men and women as other key risk factors are identified.

  1. Javad Hashemi, PhD||*,
  2. Naveen Chandrashekar, PhD,
  3. Hossein Mansouri, PhD§,
  4. Brian Gill, MD||,
  5. James R. Slauterbeck, MD,
  6. Robert C. Schutt Jr, MD||,
  7. Eugene Dabezies, MD|| and
  8. Bruce D. Beynnon, PhD